Best Weight Loss Supplements of 2024: 12 Diet Products That Actually Work

Best Weight Loss Supplements of 2024: 12 Diet Products That Actually Work

Do you feel like you don’t eat much but still aren’t losing weight? We looked at the best weight loss supplements that can help you shed pounds.

The best diet supplement we found is PhenQ, thanks to its focus on muscle growth and fat loss. Still, our review will guide you toward choosing the best option for your specific needs.

Best Weight Loss Supplements 

• PhenQ - Best weight loss supplements overall
• KetoCharge - Best for keto dieters 
• Phen24 - Best for day-and-night support 
• PrimeShred - Best for men
• CalmLean - Best stimulant-free option
• Brutal Force ACUT - Best Anavar alternative
• Brutal Force WINCUT - Best Winstrol alternative
• Trimtone - Best metabolism booster
• Instant Knockout Cut - Best for active people
• Zotrim - Best for suppressing appetite

1. PhenQ - Best Weight Loss Supplements Overall

Pros 

• Capsimax promotes fat burning
• Offers multiple weight loss benefits
• Innoslim helps reduce cravings
• Caffeine boosts energy levels

Cons 

• Some ingredients are part of proprietary blends, which do not list the exact doses

Who Is PhenQ Best For?

PhenQ is one of the best weight loss supplements for people who need extra fat-burning support since it has thermogenic effects and a multi-pronged approach.

It may suppress your appetite, elevate your energy levels, and burn body fat. It contains ingredients such as a-Lacys Reset, Capsimax powder, caffeine, chromium picolinate, L-carnitine fumarate, and nopal.

Capsimax increases markers of thermogenesis and reduces fat accumulation. It may prevent weight gain during a high-fat diet [1].

Who Should Avoid PhenQ?

• Caffeine-intolerant folks

Dosage

• 1 capsule in the morning and 1 during lunch time

Cost

• 1 bottle: $69.99
• 2 bottles + 1 free: $139.98
• 3 bottles + 2 free: $209.97

Summary

PhenQ is one of the best weight loss supplements made from thermogenic ingredients that raise your body temperature to accelerate metabolism and enhance fat burning. 

>>Check the best price for PhenQ

2. KetoCharge - Best for Keto Dieters

Pros 

• Promotes ketosis
• May reduce the side effects of keto diet
• Calcium and magnesium may enhance bone and muscle health
• Minimizes cravings

Cons 

• Does not contain potassium 
• No specific doses of each ingredient are listed

Who Is KetoCharge Best For?

KetoCharge is one of the best weight loss supplements for people who aim to enhance ketosis while following the keto diet.

It also reduces or eliminates the “keto flu.” This includes symptoms such as muscle cramps and poor concentration due to a fall in the electrolyte minerals sodium, potassium, calcium, and magnesium [2].

Who Should Avoid KetoCharge?

• People not on a keto diet

Dosage

• 2 capsules before breakfast

Cost

• 1-month supply: $59.99
• 2-month supply + 1 free: $119.99
• 3-month supply + 3 free: $179.99 

Summary

KetoCharge is counted among the best weight loss supplements that help induce and maintain a state of ketosis to make the keto diet more effective.

>>Check the best price for KetoCharge 

3. Phen24 - Best for Day-and-Night Support

Pros 

• Serotonin-boosting ingredients in the night formula 
• Guarana may boost energy in the day 
• Contains essential B vitamins for energy production
• May help reduce cravings

Cons 

• Serotonin-boosting ingredients may react with antidepressants

Who Is Phen24 Best For? 

Phen24 combines the best weight loss supplements for people who need energy during the day and relief from cravings at night.

The daytime capsules include caffeine, iodine, cayenne powder, l-phenylalanine, and guarana extract to boost metabolism and energy. The nighttime formula includes chromium, vitamin B6, Griffonia, green tea, choline, hops, and glucomannan.

Griffonia is a unique herbal extract in that it is rich in 5-HTP, the precursor to serotonin. The calming, mood-lifting effect of serotonin is often what you’re seeking when you crave sugary foods so you don’t feel the need to binge late at night [3].

Additionally, vitamins B1, B5, and B6 and biotin are essential for producing energy from sugar. Vitamin C helps your body to make carnitine, which promotes fat burning for energy [4].

Who Should Avoid Phen24?

• Individuals taking antidepressants

Dosage

• 1 capsule of the day formula and 2 capsules of the night formula

Cost

• 1-month supply: $69.99
• 2-month supply + 1 free: $139.99
• 3-month supply + 2 free: $209.99

Summary

Phen24 is unique among the best weight loss supplements since the dual package supports your day and night metabolism.

>>Check the best price for Phen24

4. PrimeShred - Best for Men 

Pros 

• Coffee and green tea extracts for fat-burning
• B vitamins for cellular energy production 
• Cayenne pepper boosts thermogenesis 
• Suitable for vegans and vegetarians 
• May enhance focus

Cons 

• May interact with dopamine-boosting medication 

Who Is PrimeShred Best For? 

PrimeShred is the best weight loss supplement for men who need a weight loss supplement that can burn fat, preserve muscles, and provide extra motivation and energy.

It includes green tea extract, caffeine, vitamin B complex, rhodiola rosea root, and L-tyrosine that boost metabolism, suppress appetite, and increase energy levels.

A combination of caffeine and rhodiola can effectively enhance dopamine, a neurotransmitter involved in motivation and neuromuscular function. Caffeine also raises adrenaline, while rhodiola boosts red blood cells and energy production to improve strength [5].

Who Should Avoid PrimeShred?

• Individuals who take ADHD meds or other prescription medications that increase dopamine

Dosage

• 3 capsules before breakfast

Cost

• 1 bottle: $59.99
• 2 bottles + 1 free: $119.98
• 3 bottles + 2 free: $179.97

Summary

PrimeShred is one of the best weight loss supplements for men aiming for fat loss while wishing to preserve muscle mass.

5. CalmLean - Best Stimulant-Free Option 

Pros 

• No caffeine or other stimulants 
• Capsaicin promotes thermogenesis
• Boosts metabolism
• Reduces cravings

Cons 

• May not offer multiple weight loss benefits

Overview

CalmLean, produced by PrimeGENIX, is a natural fat burner thatDon’t worry if caffeine and guarana give you the jitters; CalmLean is a gentler alternative to other best weight loss supplements since it has no stimulant ingredients.

Who Is CalmLean Best For? 

CalmLean is considered the best weight loss supplements for those who can’t stand stimulants such as caffeine. The formula promotes thermogenesis to facilitate weight loss.

It relies on ForsLean, a type of Coleus forskohlii extract. This herbal remedy can help reduce insulin, which promotes fat accumulation. 

Not only does it help you burn fat, but C. foskohlii can also protect lean mass and reduce waist circumference [6]. 

Who Should Avoid CalmLean?

• Those looking for caffeine’s performance-boosting benefits

Dosage

• 2 capsules daily

Cost

• 1 bottle: $59.95
• 3 bottles: $169.95
• 6 bottles: $319.95 

Summary

CalmLean presents a stimulant-free formula for those aiming to lose weight without the typical jittery feelings or other side effects associated with stimulant-based weight loss supplements.

6. Brutal Force ACUT - Best Anavar Alternative

Pros 

• Promotes thermogenesis
• Boosts lean muscle growth and energy levels
• Suppresses appetite with konjac root
• Gluten and soy-free formula
• Legal Anavar alternative

Cons 

• Contains soy and dairy products 

Who Is Brutal Force ACUT Best For? 

We recommend Brutal Force ACUT for individuals aiming to shed excess fat while retaining muscle mass, especially during bodybuilding or cutting cycles. It has similar effects to the anabolic steroid Anavar.

Branched-chain amino acids (BCAAs) may prevent muscle loss during a low-calorie diet [7].

Whey protein is high in cysteine, an amino acid that your body uses to make its own antioxidants to protect your muscles during intense exercise [8]. 

Who Should Avoid Brutal Force ACUT?

• People with soy or dairy allergies

Dosage

• 3 capsules after workouts 

Cost

• 1-month supply: $64.99
• 3-month supply: $129.98

Summary

Brutal Force ACUT emerges as a top choice among weight loss supplements. It encourages fat loss, muscle retention, and enhanced workout performance. It is a low-risk and legal alternative to the steroid Anavar.

7. Brutal Force WINCUT - Best Winstrol Alternative

Pros 

• Designed for cutting and achieving a lean appearance
• Boosts cellular energy production and metabolism
• Low-risk Winstrol alternative 
• No caffeine 

Cons 

• Only a few active ingredients 

Who Is Brutal Force WINCUT Best For?

Brutal Force WINCUT is particularly suited for assisting athletes and bodybuilders in their cutting cycles. It can help shed body fat, retain lean muscle, and improve their overall physique. It is a legal and low-risk alternative to the steroid Winstrol (Stanozolol).

One of its ingredients is acetyl-l-carnitine, which can boost fat burning for energy to increase your exercise performance [9]. 

Who Should Avoid Brutal Force WINCUT?

• Caffeine-sensitive persons

Dosage

• 2 capsules before exercise

Cost

• 1-month supply: $64.99
• 3-month supply: $129.98 

Summary

Brutal Force WINCUT shines as a low-risk alternative to the steroid Winstrol.

8. Trimtone - Best Metabolism Booster

Pros 

• Speeds up metabolic rate
• Contains glucomannan to tame cravings
• Caffeine boosts energy levels and thermogenesis
• Simple dosage

Cons 

• It may reduce medication and nutrient absorption 

Who Is Trimtone Best For?

Trimtone is ideal for women who plan to accelerate their weight loss journey by boosting their metabolism. These best weight loss supplements can help curb their appetite, burn fat, and provide extra energy

Grains of paradise can enhance thermogenesis, the energy production as heat, by increasing your body’s proportion of brown fat. This type of fat generates energy, while white fat does not [10].

Additionally, green tea may assist weight loss in women with polycystic ovarian syndrome (PCOS), a condition that features stubborn excess body fat. In a study, women lost an average of 2.8 kilograms thanks to green tea extract, reducing their risk of developing metabolic syndrome [11].

Who Should Avoid Trimtone?

• Individuals taking prescription medications

Dosage

• 1 capsule before breakfast

Cost

• 1 bottle: $59.99
• 2 bottles + 1 free: $119.98
• 3 bottles + 2 free: $179.97 

Summary

Trimtone may help you lose unwanted weight by revving up your metabolism and protecting your health long-term.

9. Instant Knockout Cut - Best for Active People

Pros 

• Vitamin D supports bone health
• Cayenne and green tea promote fat burning 
• Vitamins B6 and B12 encourage red blood cell production
• Vegetarian and vegan-friendly

Cons 

• Glucomannan may interfere with medication absorption 

Who Is Instant Knockout Cut Best For?

Instant Knockout Cut is one of the best weight loss supplements for active individuals aiming to cut weight and get in shape swiftly. The formula may heighten metabolism and energy levels.

Cayenne pepper and black pepper extracts have been studied for their metabolic, antioxidant, and anti-inflammatory effects.

Additionally, pepper extracts may have thermogenic, insulin-regulating, and cholesterol-lowering effects, especially alongside caffeine and green tea extract [12]. 

Who Should Avoid Instant Knockout Cut? 

• Persons taking narrow therapeutic index (NTI) medications 

Dosage

• 1 capsule 4 times a day

Cost

• 1 bottle: $45
• 2 bottles: $90
• 3 bottles + 1 free: $135 

Summary

Instant Knockout Cut is one of the best weight loss supplements for physically active men and women that helps burn fat and protects lean mass during vigorous exercise.

10. Zotrim - Best for Suppressing Appetite

Pros 

• Guarana and caffeine enhance fat burning
• Damiana controls hunger and cravings
• Vitamins B3 and B6 support energy production 
• Efficacy backed by several studies

Cons 

• Caffeine and guarana may be overstimulating for some users

Who Is Zotrim Best For?

Zotrim is one of the best weight loss supplements for those who want to eat less by minimizing hunger pangs.

According to research, the three-herb combination of yerba mate, guarana, and damiana was found to curb appetite in overweight women, cutting calorie intake by around 17%. Caffeine, a component of guarana extract, also has thermogenic effects [13].

Who Should Avoid Zotrim?

• Caffeine-sensitive people

Dosage

Take two to three capsules of Zotrim before every meal to make the most of its fast-acting appetite-suppressant effects. Don’t take more than nine tablets per day.

Cost

• 1-month supply: $59.99
• 2-month supply + 1 free: $119.98 
• 3-month supply +  2 free: $179.97

Summary

Zotrim is an energizing, evidence-based supplement that can support your weight loss goals by suppressing your appetite.

11. Powher - Best for Women 

Pros 

• Contains the therapeutic dose of glucomannan 
• Choline for energy production 
• Caffeine has thermogenic effects 

Cons 

• Limited stock

Who Is Powher Best For?

Powher is known as the best weight loss supplements for women wishing to enhance their weight loss efforts. It focuses on reducing cravings and combating energy dips​.

Glucomannan could help reduce body fat, fasting glucose, cholesterol, and triglycerides [14].

Additionally, choline can help break down fat for use as energy and protect your muscles during weight loss. Women usually have higher percentages of body fat and a harder time building muscle than men, so choline is a useful ingredient [15]. 

Who Should Avoid Powher? 

• Individuals on NTI medications

Dosage

• 2 capsules thrice daily before meals

Cost

• 1-month supply: $65
• 2-month supply: $129
• 3-month supply + 1 free: $195

Summary

As the best weight loss supplements for women, Powher Cut provides a female-centric solution to appetite suppression and a healthy metabolism​​. 

12. Leanbean - Best Low-Stimulant Formula

Pros 

• Glucomannan can tame cravings 
• Multiple thermogenic ingredients 
• Several antioxidant ingredients 
• Low caffeine content

Cons 

• Glucomannan may reduce medication and nutrient absorption 

Who Is Leanbean Best For? 

Leanbean is the best weight loss supplements for women and men who want to lose weight but prefer to avoid high-stimulant products. It offers a gentler approach to appetite suppression and fat burning.

Green tea extract may boost calorie burning by increasing noradrenaline levels. Green coffee bean extract can increase the burning of stored fat for energy while reducing fat digestion. Plus, garcinia cambogia may limit the accumulation of new fatty tissue [16]. 

Who Should Avoid Leanbean?

• Persons taking NTI medicines

Dosage

• 2 capsules three times a day before meals

Cost

• 1 bottle: $59.99
• 2 bottles: $119.98
• 3 bottles + 1 free: $189.97

Summary

Leanbean stands out for its low-stimulant formula, which is a rarity in the weight loss supplement market.

13. Transparent Labs RECOMP - Best for Fat-Burning

Pros

• Fusion of fat-reducing ingredients
• Improves metabolism
• Tamps down appetite
• Gluten-free formula

Cons

• Subscription required for discounts

Who Is Transparent Labs Best For?

Transparent Labs RECOMP is ideal for men and women who need the best weight loss supplements that target body fat and speed up your metabolic rate to shed extra pounds.

It is made from green tea extract, l-theanine, Forslean, and Capsimax that help eliminate fat, while Bioperine makes it easier for the body to absorb these ingredients.

Who Should Avoid Transparent Labs Best?

• Those who prefer more complex supplements

Dosage

• 2 capsules twice a day before meals

Cost

• 1 bottle: $54.99 for a one-time purchase or $6 discount with a subscription

Summary

Transparents Labs RECOMP is one of the best weight loss supplements that promotes fat-burning by lessening your hunger pangs and enhancing your metabolism.

What Are Weight Loss Supplements?

Weight loss supplements are products, often in capsule form, that claim to aid in reducing body weight by suppressing appetite, improving metabolism, or blocking fat absorption. They contain a mix of vitamins, minerals, herbs, or other natural ingredients.

Types of Weight Loss Supplements

Fat Burners (Thermogenics)

The best fat burners can increase metabolism and thermogenesis to enhance calorie and fat loss. For example, green coffee bean extract can improve fatty acid transport and energy-burning rate [16].

Appetite Suppressants (Anorectics)

The best appetite suppressants work by curbing hunger signals in the brain to reduce caloric intake.

Carb Blockers

Carb blocker supplements help prevent the breakdown and absorption of carbohydrates to reduce calorie intake.

Prescription Weight Loss Drugs

Some people find that the best weight loss pills that actually work for their individual needs are prescription meds: 

• Orlistat
• Xenical
• Contrave
• Phentermine
• Belviq

Factors To Consider When Choosing the Best Weight Loss Supplements for You

Keep these factors in mind when comparing the best weight loss supplements:

• Natural and scientifically-backed active ingredients
• Manageable dosage
• Preferred supplement form
• Product cost

Ingredients Found in Over-the-Counter Dietary Supplements for Weight Loss

Here are some common ingredients in the best weight loss supplements:

• Glucomannan: Expands in water, takes up space in the stomach, and makes you more satisfied with smaller meals
• Green Tea Extract: Linked to improved appetite suppression and fat burning. Its caffeine content boosts metabolism and thermogenesis by slowing noradrenaline breakdown 
• Chromium or Chromium Picolinate: A mineral that improves blood glucose levels, aids in weight loss, and provides metabolic benefits [16]
• Cayenne Pepper: A thermogenic ingredient and antioxidant.
• L-Carnitine: An amino acid that helps transport fatty acids into the mitochondria for energy burning
• Green Coffee Extract: Contains chlorogenic acid that may lower blood pressure, prevent aging, and burn fat. Its caffeine content curbs appetite and burns fat
• Caffeine Anhydrous: A stimulant that boosts metabolism, increases fat burning, suppresses appetite, increases energy levels, and improves focus
• Forskolin: The main active component of Coleus forskohlii that aids in the release of fatty acids from stored fat [16]
• Conjugated Linoleic Acid (CLA): May increase fat metabolism and reduce body fat while preserving muscle mass

Potential Side Effects of Weight Loss Supplements

Like any dietary supplement, weight loss supplements may have potential side effects. Consult a healthcare professional if you experience any adverse effects.

Where To Buy the Best Weight Loss Supplements

It’s best to purchase the best weight loss supplements from the official product websites, instead of third-party sellers.

Frequently Asked Questions About Weight Loss Supplements

Are Natural Diet Supplements Effective for Weight Management?

Some dietary supplements for weight loss are effective for short- or long-term weight management since they contain evidence-backed ingredients.

What Is the Most Effective Weight Loss Supplement Available?

Based on our review, Brutal Force ACUT is the most potentially effective weight loss supplement available. However, the effectiveness of weight loss supplements can vary with each user.

Can Weight Loss Supplements Work Without a Healthy Diet and Exercise?

A balanced diet and regular exercise is necessary to achieve sustainable weight loss while taking supplements.

Best Weight Loss Supplements: Final Note

The best weight loss supplements that actually work feature a combination of ingredients backed by scientific evidence to address various aspects of weight loss.

PhenQ stands out as our top pick because it enhances muscle energy production and provides antioxidant protection to maintain lean muscle mass. That said, your best option will depend on your goals and health conditions.

References

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2. Rabast, U et al. “Loss of weight, sodium and water in obese persons consuming a high- or low-carbohydrate diet.” Annals of nutrition & metabolism vol. 25,6 (1981): 341-9. doi:10.1159/000176515
3. Rondanelli, M et al. “Relationship between the absorption of 5-hydroxytryptophan from an integrated diet, by means of Griffonia simplicifolia extract, and the effect on satiety in overweight females after oral spray administration.” Eating and weight disorders: EWD vol. 17,1 (2012): e22-8. doi:10.3275/8165
4. Tardy, Anne-Laure et al. “Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence.” Nutrients vol. 12,1 228. 16 Jan. 2020, doi:10.3390/nu12010228
5. Liu, Chang et al. “Synergistic Effect of Rhodiola rosea and Caffeine Supplementation on the Improvement of Muscle Strength and Muscular Endurance: A Pilot Study for Rats, Resistance Exercise-Untrained and -Trained Volunteers.” Nutrients vol. 15,3 582. 22 Jan. 2023, doi:10.3390/nu15030582
6. Loftus, Hayley L et al. “Coleus forskohlii Extract Supplementation in Conjunction with a Hypocaloric Diet Reduces the Risk Factors of Metabolic Syndrome in Overweight and Obese Subjects: A Randomized Controlled Trial.” Nutrients vol. 7,11 9508-22. 17 Nov. 2015, doi:10.3390/nu7115483
7. Dudgeon, Wesley David et al. “In a single-blind, matched group design: branched-chain amino acid supplementation and resistance training maintains lean body mass during a caloric restricted diet.” Journal of the International Society of Sports Nutrition vol. 13 1. 5 Jan. 2016, doi:10.1186/s12970-015-0112-9
8. Veskoukis, Aristidis S et al. “Whey protein boosts the antioxidant profile of rats by enhancing the activities of crucial antioxidant enzymes in a tissue-specific manner.” Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association vol. 142 (2020): 111508. doi:10.1016/j.fct.2020.111508
9. Bruls, Yvonne Mh et al. “Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trial.” EBioMedicine vol. 49 (2019): 318-330. doi:10.1016/j.ebiom.2019.10.017
10. Yoneshiro, Takeshi et al. “Prolonged Treatment with Grains of Paradise (Aframomum melegueta) Extract Recruits Adaptive Thermogenesis and Reduces Body Fat in Humans with Low Brown Fat Activity.” Journal of nutritional science and vitaminology vol. 67,2 (2021): 99-104. doi:10.3177/jnsv.67.99
11. Colonetti, Laura et al. “Green tea promotes weight loss in women with polycystic ovary syndrome: Systematic review and meta-analysis.” Nutrition research (New York, N.Y.) vol. 104 (2022): 1-9. doi:10.1016/j.nutres.2022.03.009
12. Dludla, Phiwayinkosi V et al. “Bioactive Properties, Bioavailability Profiles, and Clinical Evidence of the Potential Benefits of Black Pepper (Piper nigrum) and Red Pepper (Capsicum annum) against Diverse Metabolic Complications.” Molecules (Basel, Switzerland) vol. 28,18 6569. 11 Sep. 2023, doi:10.3390/molecules28186569
13. Harrold, J A et al. “Acute effects of a herb extract formulation and inulin fibre on appetite, energy intake and food choice.” Appetite vol. 62 (2013): 84-90. doi:10.1016/j.appet.2012.11.018
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15. Elsawy, Gehan et al. “Effect of choline supplementation on rapid weight loss and biochemical variables among female taekwondo and judo athletes.” Journal of human kinetics vol. 40 77-82. 9 Apr. 2014, doi:10.2478/hukin-2014-0009
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